With the increased knowledge of anatomy came also corresponding advances in surgery, and many experimental operations are said to have been performed upon condemned criminals who were handed over to the surgeons by the Ptolemies. While many modern writers have attempted to discredit these assertions, it is not improbable that such operations were performed. In an age when human life was held so cheap, and among a people accustomed to torturing condemned prisoners for comparatively slight offences, it is not unlikely that the surgeons were allowed to inflict perhaps less painful tortures in the cause of science. Furthermore, we know that condemned criminals were sometimes handed over to the medical profession to be "operated upon and killed in whatever way they thought best" even as late as the sixteenth century. Tertullian[1] probably exaggerates, however, when he puts the number of such victims in Alexandria at six hundred.

Had Herophilus and Erasistratus been as happy in their deductions as to the functions of the organs as they were in their knowledge of anatomy, the science of medicine would have been placed upon a very high plane even in their time. Unfortunately, however, they not only drew erroneous inferences as to the functions of the organs, but also disagreed radically as to what functions certain organs performed, and how diseases should be treated, even when agreeing perfectly on the subject of anatomy itself. Their contribution to the knowledge of the scientific treatment of diseases holds no such place, therefore, as their anatomical investigations.

Half a century after the time of Herophilus there appeared a Greek physician, Heraclides, whose reputation in the use of drugs far surpasses that of the anatomists of the Alexandrian school. His reputation has been handed down through the centuries as that of a physician, rather than a surgeon, although in his own time he was considered one of the great surgeons of the period. Heraclides belonged to the "Empiric" school, which rejected anatomy as useless, depending entirely on the use of drugs. He is thought to have been the first physician to point out the value of opium in certain painful diseases. His prescription of this drug for certain cases of "sleeplessness, spasm, cholera, and colic," shows that his use of it was not unlike that of the modern physician in certain cases; and his treatment of fevers, by keeping the patient's head cool and facilitating the secretions of the body, is still recognized as "good practice." He advocated a free use of liquids in quenching the fever patient's thirst - a recognized therapeutic measure to-day, but one that was widely condemned a century ago.